Talk of the Nation

March Madness is officially here. Starting Tuesday, 68 college teams will compete for a spot at the NCAA men's championship on April 8. As millions across the country fill out brackets and enter office pools, this season has left longtime sports columnist Dave Kindred yearning for the good old days.

In a piece in The Washington Post, he argues that college basketball has lost its way.

Microbes may once have happily existed on the surface of Mars, according to chemical analysis of a sedimentary rock in the Red Planet's Gale crater. NASA geologist and exobiologist David Blake discusses evidence for an ancient freshwater lake in the crater, and describes the mineral-chomping microbes that may have thrived there.

By combing through 100 million search queries on Bing, Yahoo and Google, Microsoft Research Lab co-director Eric Horvitz and his colleagues were able to discover a previously unknown interaction between two commonly prescribed drugs. Horvitz says the method might detect dangerous drug interactions earlier than the FDA's warning system.

Kathy Reichs, the writer and scientist behind the TV show Bones, is back with a new novel for young adults. Code: A Virals Novel stars Tory Brennan, great-niece of Reich's famed crime-solving heroine Tempe Brennan. Reichs discusses the book, co-written with Brendan Reichs.

After Vice President Joe Biden used the term "malarkey" in a 2012 debate, searches for the word in online dictionaries surged. Now that dictionaries are readily available with a mouse click or finger tap, dictionary publishers can track the correlation between word searches and current events.

NPR's Neal Conan reads from listener comments on previous show topics, including social mobility, romantic comedies, and Japan's recovery from the earthquake and tsunami in 2011.

North Korea scrapped the 1953 armistice agreement that ended the Korean War, escalating fears of a preemptive nuclear attack on the U.S. Tuft University Korean studies professor Sung-Yoon Lee discusses this precarious moment for North Korea, its neighbors and the international community.

Jurors in a New York federal court found a former New York City police officer guilty of plotting to kidnap and cook his wife and other women. The defense argued that Gilberto Valle never acted on his fantasies, and described the verdict as a case of thought prosecution.

Cardinals at the Vatican chose Argentine cardinal Jorge Mario Bergoglio as the new pope. He will take the papal name Francis and is the first pope from South America. NPR's Neal Conan talks with guests about the significance of the event around the world.

From the ongoing budget battle to Sen. Carl Levin's retirement announcement, NPR's Political Junkie Ken Rudin recaps the week in politics. NPR's Phillip Reeves provides an update from Rome as cardinals elected a new pope.